I have (had) a long history over several decades of multiple illness "diagnoses" including chronic fatigue syndrome --all of which, when you dug into them, were of unknown or "idiopathic" origin. I'll spare you the long history and complicated explanations that finally emerged, because you really don't need them, but I would have died years ago if I hadn't figured it all out, and almost did die several times along the way. My problems were serious enough that at one point the doctors in the hospital told me I'd be dead in 24-48 hours, if things didn't improve. They did an operation on me once that had multiple risks of death ranging up to 40 percent each, but they said if they didn't do it, there was a 100 percent certainty I would die. But they were powerless to pinpoint causes or actually cure anything. I left the hospital against the arguments of three of them, and set out learning how to heal myself, which eventually I did.
What you do need to know, to help your wife, is where the CURE to MOST diseases lies, in the diet. Before you dismiss this, and sparing you another encyclopedia-long explanation, just TRY what I'll outline here for three months. Thank me later.
First, your wife must STOP eating all grain foods (except white rice), dairy products, and ALL factory-processed/maufactured foods. That means nearly every food that comes packaged in a can, jar, box or pre-printed wrapper/container. Eliminate every food that lists ingredients including additives or chemical names, even if the packages make health claims and say some of the ingredients are called "organic" or "natural". Do all your food shopping in the wet markets and/or the outer "fresh foods" section of the supermarkets. [There are a FEW minor exceptions to these rules, like fresh, raw nuts that may come in a bag/package, but basically follow this and you'll be safe.]
Basically, you need to emphasize foods that not only your great-grandmother would have recognized, but your ancestors from 30,000 years ago, before the agricultural age would also recognize. That means fresh, leafy greens (spinach and kale are excellent); vegetables (the more variety, the better); fruits (forget the nonsense about sugars; when you eat the whole fruit, it's fine); and nuts (NOT cashews or peanuts, but others like walnuts, almonds and pecans).
Eat these foods about 75% raw and 25% cooked. Two big salads and one meal of steamed veggies with rice is a good start. Eat as much as appetite dictates, but no more. Typical meals should be about the size of two fists held together, which approximates the size of the stomach. Chew the food well. Consider getting a Vita-Mix blender, to liquefy foods into smoothies.
Include some good natural fats like fresh coconut, avocado, and olives ( if you can't get fresh, rinse well to remove as much of the preservative salt as possible first). Use only coconut oil to cook in. A little bit of extra-virgin olive oil or fresh walnut oil or avocado oil or hemp oil is okay on a salad, but for cooking purposes, avoid other oils than (cold-pressed) coconut oil.
Add medicinal foods and spices to the diet, including beets, garlic, ginger, and turmeric (take with a little bit of black pepper). There are other good ones, but these are the best "must haves" to start with.
DO NOT CHEAT, NOT EVEN A LITTLE. I cannot over-emphasize this. When I started healing, even something as apparently innocuous as a splash of soya sauce or a piece of sushi made me ill, and undid all the effects of the diet for days. If your wife has a gluten issue (VERY common now with modern strains of genetically altered wheat!), even a few parts-per-million can set off negative consequences. AFTER the three months, she can start testing foods again, but not before.
Get enough rest. Sleep early - absolutely not later than 10 pm. Let the helper take care of the kid during the night, not the sick mother, until she is healed. Make the bedroom as dark and quiet as possible. Deep sleep is essential for true healing, which is why you never want to be in a hospital when you are really sick.
Drink FILTERED water only, not tap water, even if it is boiled. Do NOT drink bottled water from plastic containers. Get glass containers and refill them with your own filtered water, to drink when you are out of the house.
Add a filter to your shower, so you aren't showering with as-is tap water.
STOP using regular flouridated toothpastes. Go to an Indian Provisions store and buy an ayurvedic toothpaste like Vicco or Dabur Red. While you are there, also buy a bottle of sesame oil (Note: do NOT use the Chinese type in the supermarkets!) and start "oil pulling". Basically, each morning before eating anything you swish a tablespoon of the oil around your teeth and gums for 15-20 minutes. Then spit the oil out (do NOT swallow it - it will be full of harmful bacteria!). Rinse and brush with an acceptable toothpaste. If you have a tongue scraper, use it also.
Start deep, slow breathing. Breathe into the abdomen from the diaphragm, hold it a few seconds (do NOT strain!) and exhale at a comfortably slow pace. You can do this for 5 minutes, or 5 hours, whatever feels good. Do not chest-breathe or hyperventilate; it should feel good and make you feel cleaner, not dizzy.
Consider trying meditation and relaxation and visualization exercises. Without the dietary changes, these may not be effective, but in combination these can speed up healing, too.
This may seem like a lot, but start with the diet. That's the huge elephant in the room, so to speak. Then add as many of the other things as you can. There is more that can be done, but if you do nothing other than fix the diet, the rest may not matter much. Keep eating the processed, factory "foods" and it will be almost impossible to fully heal.
Good luck. If you need to know more, send me a message c/o this site and I'll do what I can to help you.
OH! A word about meats. Avoid them in the initial healing period. They can be added back in later, but not the processed kinds with preservatives, and not the meats from factory-raised animals fed grains and treated with antibiotics and hormones. Processed meats in plastic in the supermarket, unless otherwise labelled, usually have gluten in them, so avoid them like the plague for now. Avoid all meats with nitrates or nitrites in them --but you know that already, since you are avoiding all additives. Right?! (grin) When you do eventually want to eat them, look for organic, grass-fed or pastured meats. Organ meats and liver are actually excellent foods, but probably best saved for the post-healing, rebuilding phase.
Eggs, on the other hand, are excellent, but ONLY the organic, pasture-fed ones (sorry, they are much more expensive!), and then do not fry or scramble them. Raw is best (after a good washing of the shell!), but they can be boiled (preferably soft-boiled) or poached.
Okay, there is more, but this should be ample to get your wife into "healing mode". If she tries to tweak a little around the edges, it probably won't work. I wasted YEARS trying to heal with conventional wisdom and little tweaks, and only continued to suffer more and more. It takes a dramatic, full, no-cheating change to effect deep healing, but once you've experienced it, you'll never look at the world the same way again. Expect a miracle, because if you do all this as described, the difference (even if you are "normal" and not sick to begin with) will be darned near miraculous!