Booster Shot insanity

Posted by Ed 5 mths ago
Before you even CONSIDER a third shot, please read this

As Covid cases, hospitalizations, and now deaths soar in Israel even though over 90 percent of older adults are fully vaccinated, the country is aggressively pushing a third shot.

Hundreds of thousands of older Israelis have already received it.

And other countries are preparing to follow.

Now the inevitable is happening. The third shot is beginning to fail.
US Hospitalizations Surge (Image Wall St Journal)

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Ed 5 mths ago
Israel Warns COVID 'Green Pass' Will Expire If Residents Don't Get Third Jab 
Israel’s government has expanded availability of controversial Covid-19 vaccine booster shots to all inoculated residents 12 and older and decreed that those who decline the third jab will soon lose their “green pass” privileges.

The move, announced on Sunday, marked the fourth time this month that Israel has expanded eligibility for vaccine booster shots. Initially rolled out on August 1, the booster campaign was then limited to people 60 and older. The minimum age was dropped to 30 last week.

“The third complementary vaccine works,” Prime Minister Naftali Bennett said on Sunday. “Two million Israelis have already been vaccinated [with a third dose].”

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Ed 5 mths ago
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Ed 5 mths ago
Virus czar calls to begin readying for eventual 4th vaccine dose
Salman Zarka says COVID-19 is here to stay for and that next booster shot may be adjusted for variants: ‘This is our life from now on, in waves’

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Ed 4 mths ago
Study: COVID Shot Enhances Delta Infectivity
  • According to the U.S. Centers for Disease Control and Prevention, people who got the COVID shot early are now at increased risk for severe COVID disease
  • This may be a sign that antibody dependent enhancement (ADE) is occurring, or it may simply indicate that the protection offered is limited to a few months, at best
  • Recent research warns the Delta variant “is posed to acquire complete resistance to wild-type spike vaccines.” This could turn into a worst-case scenario that sets up those who have received the Pfizer shots for more severe illness when exposed to the virus
  • To “stay ahead of the virus,” the Biden administration is now considering recommending a booster shot five months after the initial two doses rather than waiting eight months, as previously suggested
  • Israeli data show Pfizer’s shot went from a 95% effectiveness at the outset to 39% by late July 2021, when the Delta strain became predominant. The U.S. Food and Drug Administration’s expectation for any vaccine is an efficacy rate of at least 50% compared to placebo


The official COVID-19 vaccine narrative changes rapidly these days. It took just one month for it to go from “if you’re vaccinated you’re not going to get COVID,”1 including the Delta variant,2 to “people who got vaccinated early are at increased risk for severe COVID disease.”3

From the get-go, I and many other medical experts have warned of the possibility of these shots causing antibody dependent enhancement (ADE), a situation in which the shot actually facilitates a cascade of disease complications rather than protects against it. As a result, you may suffer more severe illness when encountering the wild virus than had you not been “vaccinated.”

While we don’t yet have definitive proof that ADE is occurring, we are seeing suspicious signs that it might be. Data showing those who got the shot early this year are now at increased risk of severe infection could be such a sign. At bare minimum, it’s an indication that the protection you get from these shots is very temporary, lasting only a few months.

This makes sense when you consider they program your body to produce just one type of antibody against a specific spike protein. Once the spike protein, or other elements in the virus, starts to mutate, protection radically diminishes. Worse, the vaccine facilitates the actual production of the variants because it is “leaky” and provides only partial ineffective immune protection.

Natural immunity is far superior, as when you recover from the infection, your body makes antibodies against all five proteins of the virus, plus memory T cells that remain even once antibody levels diminish. This gives you far better protection that will likely be lifelong, unless you have impaired immune function.

Real-world data from Israel confirms this, showing those who have received the COVID jab are 6.72 times more likely to get infected than people with natural immunity.

CDC Admits ‘Vaccine’ Immunity Doesn’t Last

“’The data we will publish today and next week demonstrate the vaccine effectiveness against SARS COVID 2 infection is waning,’ the CDC director [Rochelle Walensky] began … She cited reports of international colleagues, including Israel ‘suggest increased risk of severe disease amongst those vaccinated early.’

Fear not, the same people who tried to sell Americans immunity through a jab and promised to hand back the freedoms they impeded on have a plan, and they’re not leaving much room for personal choice.

‘In the context of these concerns, we are planning for Americans to receive booster shots starting next month to maximize vaccine induced protection. Our plan is to protect the American people and to stay ahead of this virus,’ Walensky shared …

The CDC director appears to all but admit that the vaccine’s efficacy rate has a strict time limit, and its protections are limited in the ever-changing environment.

‘Given this body of evidence, we are concerned that the current strong protection against severe infection, hospitalization and death could decrease in the months ahead. Especially among those who are higher risk or those who were vaccinated earlier during the phases of our vaccination roll out,’ Walensky explained …

Starting September 20, Americans who completed their two doses of the Pfizer or Moderna vaccine at least eight months ago will be eligible for a booster shot. The goalposts back to a ‘normal’ society continue to be moved further and further. When will Americans, especially those who complied with initial vaccinations, have had enough?”

Data Reveal Rapidly Waning Immunity From Shots

Indeed, Israeli data show Pfizer’s shot went from a 95% effectiveness at the outset, to 64% in early July 2021 and 39% by late July, when the Delta strain became predominant.8,9 Meanwhile, the U.S. Food and Drug Administration’s expectation for any vaccine is an efficacy rate of at least 50%.

Pfizer’s own trial data even showed rapidly waning effectiveness as early as March 13, 2021. BMJ associate editor Peter Doshi discussed this in an August 23, 2021, blog.10

By the fifth month into the trial, efficacy had dropped from 96% to 84%, and this drop could not be due to the emergence of the Delta variant since 77% of trial participants were in the U.S., where the Delta variant didn’t emerge until months later. This suggests the COVID shot has a very temporary effectiveness regardless of new variants.

What’s more, while Israeli authorities claim the Pfizer shot is still effective at preventing hospitalization and death, many who are double-jabbed do end up in the hospital, and we’re already seeing a shift in hospitalization rates from the unvaccinated to those who have gotten one or two injections. For example, by mid-August, 59% of serious COVID cases were among Israelis who had received two COVID injections.

Vaxxed Over Age 50 at Increased Risk for Serious Infection

Data from the U.K. show a similar trend among those over the age of 50. In this age group, partially and fully “vaccinated” people account for 68% of hospitalizations and 70% of COVID deaths.12

Study COVID Shot Enhances Delta Infectivity image 1

80% of COVID Hospitalizations in Massachusetts Were Vaxxed

Data13 from the U.S. Centers for Disease Control and Prevention also raise questions about the usefulness of the COVID shots. Between July 6 and July 25, 2021, 469 COVID cases were identified in a Barnstable County, Massachusetts, outbreak.

Of those who tested positive, 74% had received two COVID injections and were considered “fully vaccinated.” Even despite using different diagnostic standards for non-jabbed and jabbed individuals, a whopping 80% of COVID-related hospitalizations were also in this group.

"Although Pfizer-BioNTech BNT162b2-immune sera neutralized the Delta variant, when four common mutations were introduced into the receptor binding domain (RBD) of the Delta variant (Delta 4+), some BNT162b2-immune sera lost neutralizing activity and enhanced the infectivity. ~ bioRxiv, August 23, 2021"

The CDC also confirmed that fully vaccinated individuals who contract the infection have as high a viral load in their nasal passages as unvaccinated individuals who get infected, proving there’s no difference between the two, in terms of being a transmission risk.

If vaccination status has no bearing on the potential risk you pose to others, why do we need vaccine passports? According to Harvard epidemiologist Martin Kulldorff, this evidence demolishes the case for passports.17 They clearly cannot ensure safety, as evidenced by outbreaks where the vaccination rate was 100%. Examples include outbreaks onboard a Carnival cruise liner18 and the HMS Queen Elizabeth, a British Navy flagship.

Study Predicts Pfizer Shot Will Enhance Delta Infectivity

A study20 posted August 23, 2021, on the preprint server bioRxiv now warns the Delta variant “is posed to acquire complete resistance to wild-type spike vaccines.” This could essentially turn into a worst-case scenario that sets up those who have received the Pfizer shots for more severe illness when exposed to the virus. As explained by the authors:

“Although Pfizer-BioNTech BNT162b2-immune sera neutralized the Delta variant, when four common mutations were introduced into the receptor binding domain (RBD) of the Delta variant (Delta 4+), some BNT162b2-immune sera lost neutralizing activity and enhanced the infectivity.

Unique mutations in the Delta NTD were involved in the enhanced infectivity by the BNT162b2-immune sera. Sera of mice immunized by Delta spike, but not wild-type spike, consistently neutralized the Delta 4+ variant without enhancing infectivity.

Given the fact that a Delta variant with three similar RBD mutations has already emerged according to the GISAID database, it is necessary to develop vaccines that protect against such complete breakthrough variants.”

Proactive Use of COVID Shots Drive Dangerous Mutations

It’s now clear that early warnings against mass vaccination during an active outbreak are being realized. It’s not the unvaccinated that are driving mutations; it’s the vaccinated, as the injections simply do not prevent infection.

The end result, if we keep going, will be a treadmill of continuous injections to keep up with the merry-go-round of waning effectiveness in general combined with the emergence of vaccine-resistant variants. As reported by Live Science:

“Vaccine-resistant coronavirus mutants are more likely to emerge when a large fraction of the population is vaccinated and viral transmission is high … In other words, a situation that looks a lot like the current one in the U.S.

The mathematical model,23 published July 30 in the journal Scientific Reports, simulates how the rate of vaccination and rate of viral transmission in a given population influence which SARS-CoV-2 variants come to dominate the viral landscape …

If viral transmission is low, any vaccine-resistant mutants that do emerge get fewer chances to spread, and thus, they're more likely to die out, said senior author Fyodor Kondrashov, who runs an evolutionary genomics lab at the Institute of Science and Technology Austria.”

These findings come as no surprise to those familiar with previous research showing the same exact thing. As explained in “Vaccines Are Pushing Pathogens to Evolve,” published in Quanta Magazine,24 “Just as antibiotics breed resistance in bacteria, vaccines can incite changes that enable diseases to escape their control.”

The article details the history of the anti-Marek’s disease vaccine for chickens, first introduced in 1970. Today, we’re on the third version of this vaccine, as within a decade, it stops working. The reason? The virus has mutated to evade the vaccine. As a result of these leaky vaccines, the virus is becoming increasingly deadly and more difficult to treat.

A 2015 paper25 in PLOS Biology tested the theory that vaccines are driving the mutation of the herpesvirus causing Marek’s disease in chickens. To do that, they vaccinated 100 chickens and kept 100 unvaccinated. All of the birds were then infected with varying strains of the virus. Some strains were more virulent and dangerous than others.

Over the course of the birds’ lives, the unvaccinated ones shed more of the least virulent strains into the environment, while the vaccinated ones shed more of the most virulent strains. As noted in the Quanta Magazine article:

“The findings suggest that the Marek’s vaccine encourages more dangerous viruses to proliferate. This increased virulence might then give the viruses the means to overcome birds’ vaccine-primed immune responses and sicken vaccinated flocks.”

Vaccinated People Can Serve as Breeding Ground for Mutations

Before 2021, it was quite clear that vaccines push viruses to mutate into more dangerous strains. The only question was, to what extent? Now all of a sudden, we’re to believe conventional science has been wrong all along. Here’s another example: NPR as recently as February 9, 2021, reported that “vaccines can contribute to virus mutations.” NPR science correspondent Richard Harris noted:

“You may have heard that bacteria can develop resistance to antibiotics and, in a worst-case scenario, render the drugs useless. Something similar can also happen with vaccines, though, with less serious consequences.

This worry has arisen mostly in the debate over whether to delay a second vaccine shot so more people can get the first shot quickly. Paul Bieniasz, a Howard Hughes investigator at the Rockefeller University, says that gap would leave people with only partial immunity for longer than necessary.”

According to Bieniasz, partially vaccinated individuals “might serve as sort of a breeding ground for the virus to acquire new mutations.” This is the exact claim now being attributed to unvaccinated people by those who don’t understand natural selection.

It’s important to realize that viruses mutate continuously and if you don’t have a sterilizing vaccine that blocks infection completely, then the virus mutates to evade the immune response within that person. That is one of the distinct features of the COVID shots — they’re not designed to block infection. They allow infection to occur and at best lessen the symptoms of that infection. As noted by Harris:

“This evolutionary pressure is present for any vaccine that doesn't completely block infection … Many vaccines, apparently, including the COVID vaccines, do not completely prevent a virus from multiplying inside someone even though these vaccines do prevent serious illness.”

In short, like bacteria mutate and get stronger to survive the assault of antibacterial agents, viruses can mutate in vaccinated individuals who contract the virus, and in those, it will mutate to evade the immune system.

In an unvaccinated person, on the other hand, the virus does not encounter the same evolutionary pressure to mutate into something stronger. So, if SARS-CoV-2 does end up mutating into more lethal strains, then mass vaccination is the most likely driver.

What NFL Outbreak Can Tell Us

As reported August 27, 2021, by MSN,29 as players were encouraged to get the COVID shot for everyone’s safety, separate testing rules were put into place. Players who have gotten the jab only need to test every two weeks, while unvaccinated players undergo daily testing.

The relaxed testing requirement for double-jabbed players was used as incentive to go ahead and get the shot. As reported by MSN, “Conversely, the continued daily testing would become part of a punitive system that would make life so annoying for the unvaccinated that they would eventually get on board.”

Well, this didn’t work out as planned. Nine Titans players and head coach Mike Vrabel have now tested positive, showing it really doesn’t matter if you’re double-jabbed or not. The infection spreads among the vaxxed just the same. As noted by MSN:

“The pandemic is in a phase where the unvaccinated are facing the vengeance of a more aggressive strain of COVID-19. It's also an era when the vaccinated are grappling with the reality that their shots are mitigating their symptoms and medical complications, but not completely preventing them from becoming infected or transmitting COVID to others.”

To remedy the matter, the NFL Players Association, the union representing players of the National Football League, is now calling for a return to daily testing of all players, regardless of COVID jab status. Time and again, we find that incentives fall far short of their initial promise. This has been the case for masks as well.

First, we were told that if we got the COVID shot, we didn’t need to wear masks anymore. Of course, universal mask recommendations returned full force when it became apparent that breakthrough infections were still occurring at a surprising rate.

Now, routine testing with a test known to produce false positives at a rate of about 97%32 is promoted again, regardless of injection status, and there’s no reason to assume the same won’t happen with vaccine passports. We’re promised freedom if we give up medical autonomy, but freedom will never actually be granted. They’ll just continue to move the goal post.

It is highly likely, in fact even predictable, that despite its dramatic ineffectiveness, the requirement for one or two COVID jabs will soon be turned into three, and vaccine passport holders who don’t want to get that third shot will be back at Square 1. They’ll be just as undesirable as those who got no shots.

Considering the speed at which SARS-CoV-2 is mutating, you can be assured there’ll be a fourth shot, and a fifth and, well, you get the idea. Vaccine passports and COVID jab requirements will simply lead to a situation where you have to keep getting additional shots or lose all your privileges.

Of course, every single injection comes with health risks, and the risk for an adverse event will probably get bigger and bigger with each additional shot, and you don’t need to be a modern-day Nostradamus to see where this will lead us.

Five-Month Booster Shot Now Under Consideration

Unfortunately, rather than accepting reality — which is that SARS-CoV-2 is here to stay, just like any number of other common cold and influenza viruses — and stopping the merry-go-round of injections that only make matters worse, President Biden said he’d spoken with Dr. Anthony Fauci about giving booster shots at the five-month mark after the initial round of injections rather than waiting eight months, as previously suggested.

While Fauci quickly responded34 that eight months was still the goal, he also said that “we are open to data as they come in” if the Food and Drug Administration and the Advisory Committee on Immunization Practices determine a sooner timeline is necessary.

Israel began administering a third booster shot to people over the age of 60 July 30, 2021. August 19, eligibility for a booster was expanded to include people over the age of 40, as well as pregnant women, teachers and health care workers, even if they’re younger than 40. Initial reports suggest the third dose has improved protection in the over-60 group, compared to those who only got two doses of Pfizer.35 According to Reuters:

“Breaking down statistics from Israel's Gertner Institute and KI Institute, ministry officials said that among people aged 60 and over, the protection against infection provided from 10 days after a third dose was four times higher than after two doses. A third jab for over 60-year-olds offered five to six times greater protection after 10 days with regard to serious illness and hospitalization.”

Anyone who thinks one or more booster shots are the answer to SARS-CoV-2 is likely fooling themselves though. I look forward with trepidation to data on hospitalization and death rates, not to mention side effect rates, in the months to come.

Knowing what we already know about the risks of these shots and their tendency to encourage mutations, it seems reasonable to suspect that all we’re doing is digging ourselves an ever-deeper, ever-wider hole that’s going to be increasingly difficult to get out of.

Source and References


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Ed 4 mths ago

Recognizing the Obvious: Hard Data from Israel Reveals Vaccine Failure

The reality on the ground, however, is a complete opposite of what one would expect.

Israel, one of the world’s most vaccinated nations, is having its worst numbers since the beginning of the pandemic.

Here is a quote from a recent report by CNBC News titled “Israel doubles down on booster shots as daily Covid cases set new record.”

“Covid-19 cases in Israel have been rising sharply since July despite the high vaccination rate. New daily cases in the country reached an all-time high of 12,113 on August 24, surpassing the January peak of 11,934.”

This situation is confirmed by a piece on NPR:

“Israel was the first country on Earth to fully vaccinate a majority of its citizens against COVID-19. Now it has one of the world’s highest daily infection rates — an average of nearly 7,500 confirmed cases a day, double what it was two weeks ago. Nearly one in every 150 people in Israel today has the virus.”

And here is an account from an Israeli news outlet:

“The country has one of the world’s highest COVID-19 vaccination levels, with about 78 percent of those ages 12 and older fully vaccinated, mostly with the Pfizer vaccine. At the same time, Israel now has one of the highest infection rates in the world…” [emphasis added]

Let us spell out what is transpiring in Israel these days: fully vaccinated people are getting infected with Covid-19 and are in turn infecting other fully vaccinated people with this disease.

Israel Now Has More COVID Infections Per Capita Than Any Country in the World, Even as “Booster Shots” Are Being Widely Administered There

Please ponder this carefully and then ask yourself this question: what can we conclude from the fact that one of the world’s most vaccinated countries has one of the world’s highest Covid infection rates?

Here is the inescapable conclusion: the vaccines that have been injected into the people of Israel have failed to protect them against Covid-19.

To put it another way, the Pfizer vaccine that has been widely used in that country has been shown to be ineffective.

The government of Israel recognized as much when it began administering boosters on July 30. The boosters are nothing less than the admission by the Israeli health authorities that the original vaccines do not fulfil their protective function.

They have, in fact, admitted as much when confronted with real-world data:

“Announcing the decision on Sunday, top Israeli health officials said the effectiveness of the second dose of the Pfizer-BioNTech vaccine waned six months after administration, making a booster necessary.”

According to Dr Kobi Haviv, Director of Herzog Hospital in Jerusalem, fully vaccinated people account for 85-90 percent of hospitalizations at his institution. Given that less than that percentage of the Israeli population is fully vaccinated, it would seem that vaccination not only does not prevent you from contracting the disease, but may actually increase one’s chances of becoming a serious Covid case.

The figures from Israel also show that vaccinated people are 27 times more likely to contract symptomatic Covid than those who have acquired natural antibodies through infection.

Rather than being a success, the much-touted Israeli’s vaccination drive has been an abysmal failure.

This is the inescapable conclusion of the hard data before us.

Most people, however, are unable to see this obvious truth, because they have been brainwashed into believing that the vaccines are the way out of the pandemic. The vaccines propagandists have been able to induce cognitive dissonance in their victims.

It is sad and disturbing to see these very victims lining up lamb-like for their “boosters” which are manufactured by the same companies and people responsible for this debacle.

After eighteen months of relentless fearmongering and propaganda their cognitive ability has been impaired to the point that they cannot make logical sense of the information before their eyes.

What’s worse, these vaccines are not merely ineffective. Reports of severe side effects and injuries have been pouring in from all over the world. According to a report issued by the Israeli People’s Committee (IPC), a citizen-led group of Israeli health experts, the Pfizer/BioNTech vaccine has the potential to damage virtually every system in the human body. Based on data drawn from the Central Bureau of Statistics and the Israeli Ministry of Health, the group estimates that the mortality rate among the vaccinated is about 1:5000. This would mean that more than a thousand Israeli citizens died needlessly because of the vaccines.

Let us recap what we know beyond any doubt: one of the most vaccinated countries is currently posting one of the highest rates of infection in the world.

What deduction can we make based on these two widely reported and undeniable facts?

It is truly regrettable that most people today fail to see the obvious truth that stares us right in the face.

Since we are all being forced to take the vaccine, we urge everyone to consider the reality before our eyes.

The evidence coming from Israel glaringly exposes the dire fact: the Pfizer vaccine does not work. It does not shield its recipients from Covid-19.

Pfizer, however, is not the only failing vaccine. Quite to the contrary, it appears to be one of the most “effective” available, which is one of the reasons why it was the first one to receive full approval from the Food and Drug Administration (FDA).

Please carefully ponder the full implications of this.


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Ed 4 mths ago
Most Covid patients at Israeli hospital fully vaccinated? What does this mean for Australia?

Israel has been held up as the “gold standard” of how to conduct the coronavirus vaccine rollout. It has seen approximately 70% of its population receive the jab. The Israelis have relied in the main on the Pfizer vaccine.

 However, recently the country’s Prime Minister, Naftali Bennett, stated that the Pfizer vaccine is ‘significantly less’ effective against the so-called Delta variant. This follows on from a statement last June by Ran Balicer, who leads an expert advisory panel for the Israeli government, in announcing that the country might end up in lockdown again.
Balicer and other officials said that 90 per cent of the new cases were caused by the Delta variant.

Now an Israeli doctor has revealed a bombshell during a television interview. In the interview on August 5 with Israel’s Chanel 13, Dr Kobi Haviv, medical director of Herzog Hospital in Jerusalem, stated that the majority of coronavirus patients in an Israeli hospital are fully vaccinated, including those with severe disease.

Dr Haviv further specified that: “95% of the severe patients are vaccinated,” adding “85-90% of the hospitalizations are in fully vaccinated people” and the hospital is “opening more and more COVID wards.” This has led him to conclude that “the effectiveness of the vaccine is fading out.”

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Ed 4 mths ago
10/12/2020 — Fauci predicted herd immunity by next fall and “normality” by 2021's end, as long as enough people get vaccinated to bring the pandemic to an end. 
We were told the vaccines were 'thoroughly tested' 
Israel has a 90% full vaccination rate. 
Where's the herd immunity?

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Ed 3 mths ago

The Booster Shots Will Make the Crisis Worse

Israel got an early start on vaccinating its population and began offering a third dose of mRNA vaccine in July to the older age group (≥ 60 years). The results from an observational study comparing the clinical outcome of participants who received a third shot to those in the same age group who had received only two shots over the same period clearly indicated that the risk of severe disease dropped by a factor of almost 20. Additionally, those who received the third dose were also enjoying some level of protection against infection as they were also less likely to test positive for SARS-CoV-2 (1).

These are strong results, and at first glance many of those within this age group and not yet boosted might feel ashamed for their indifference in protecting themselves and others! However, there is a catch, and it’s not about potential biases in the analysis of the study results, or criticism from a public health perspective of delivering additional shots to individuals while many others have not even had their first.

The caveat is much more fundamental and has to do with immunology: a discipline that seems to have been largely reduced since the crisis began to measuring antibodies (Abs) in the blood. The results above were obtained after a very short observation period (12 days), and there is no data yet on the long-term outcome of repeated booster immunizations. This prompts an interesting question: could the immune-protective effect observed within 2 weeks of a booster injection trigger a short-term replenishment of the ‘lost’ protection against infection while at the same time not translating into long-term protection against infection or disease? The answer is most definitely ‘yes’ and can only be understood if one brings into play the single most important confounder of all Covid-19 vaccine efficacy studies conducted thus far: innate immunity.

It is well known that, regardless of any induced antigen (Ag)-specific adaptive immune response, all vaccines (including mRNA vaccines) have an adjuvant effect: they stimulate innate immune effectors, some of which have antiviral activity and/or facilitate adaptive immunity (2, 3, 4).

Without going into mechanistic detail, there is no doubt that some of these innate, nonAg-specific immune responses have a short-lived antiviral effect. This could already explain why booster doses in the population described above can prevent viral infection while recalling anti-spike Abs. It may also be tempting to assume that these recalled Abs are now responsible for enhanced protection from both infection and disease.

However, from an immunological viewpoint, it is difficult to understand how a rapid recall of the very same anti-S Abs in a previously vaccine-primed population would now all of a sudden enable better protection from infection and disease. If innate immunity is indeed the confounder, then the outcome of long-term surveillance studies would look very different. Given the more potent neutralizing Abs booster shots are generating against variants (5), the S(pike)-directed immune pressure in the population will only continue to rise while still failing to curtail the spread of the predominantly circulating highly infectious SARS-CoV-2 variant (e.g., Delta variant).

On the contrary, it would be reasonable to assume that upon an additional booster shot the more potent Abs further contribute to selecting S-directed immune escape variants and, therefore, turn the previously primed population in an even more fertile breeding ground for the highly infectious Delta variant.

As vaccine-elicited Ab responses have a much longer duration (and can be memorized) than that induced by short-term innate immune activation, and as vaccinal Abs suppress the functional capacity of pre-existing CoV-reactive innate Abs, short-term vaccine-mediated innate immune protection against viral infection or disease does not automatically imply a positive effect of the vaccine on viral infection or morbidity rates in the longer term.

Interpretations from scientists who only conduct short-term surveillance studies in vaccinees, the majority of whom are adults or elderly, lead to erroneous, although peer-reviewed conclusions such as: ‘Although vaccines are less effective against asymptomatic disease (*) or against transmission than against severe disease, even in populations with fairly high vaccination rates the unvaccinated are still the major drivers of transmission and are themselves at the highest risk of serious disease’ (6). This clearly illustrates their lack of understanding of the contribution of innate immunity in providing short-term protection after vaccination, and in the more durable protection of young and healthy unvaccinated age groups.

Based on all of the above, it is reasonable to expect booster injections to only enable the virus to more rapidly evolve resistance to the vaccines. This evolution would be dramatically expedited by vaccinating and boosting more and more younger age groups. More potent anti-S Abs induced by additional booster injections will further erode their innate Ab-mediated immunity and accelerate the pace at which SARS-CoV-2 evolves from more infectious variants into variants that increasingly escape from neutralizing anti-S Abs.

The single earliest and most potent indicator for such an unfortunate evolution would be a failure of the infection rate to drop below a relatively high baseline level. A peak of cases that tails off at a fairly elevated baseline level of viral infectivity in the population would reflect the diminished sterilizing immune capacity of the unvaccinated population. It is reasonable to assume that when the booster-mediated, nonAg-specific innate immune activation wanes, the vaccinees will resume their breeding of more infectious variants (e.g., Delta variant) and become more susceptible to Covid-19 disease.

At the same time, the resulting growth in infectious pressure would also increase the likelihood for unvaccinated, previously asymptomatically infected individuals to become more rapidly re-exposed to the virus. This would contribute to a further rise of the infection rate in the population and, therefore, also augment the susceptibility of the unvaccinated to Covid-19 disease.

Israel’s top virologist, Dr. Rivka Abulafia-Lapid, is convinced that the booster will keep existing variants under control and prevent the spread of other variants for around 6 to 8 months. She believes that Israel is currently witnessing the end of the fourth surge as a result of 3 million people taking a booster (7). A more thorough understanding of the interplay between the virus and host immunity at a population level clearly predicts, however, that the infection rate will not only halt its decrease but will also tail off at a level that is much higher than previously seen before while preparing for the next large surge in cases (see graph below).

More specifically, Israel’s booster efforts are likely to generate a spectacular surge of morbidity and mortality rates in the population as a combined result of increased S-directed immune selection pressure in vaccinees (i.e., optimizing the breeding ground for the Delta variant) and enhanced infectivity rates in the unvaccinated.

From a scientific viewpoint it is, therefore, difficult to understand how booster immunizations using vaccines which are not evolution-proof could prevent a highly mutable virus from escaping neutralizing anti-S Abs while driving the pandemic in a catastrophic direction, both in Israel and worldwide.

How can the WHO stand by and watch as this additional experiment unfolds, soon to be followed by other countries?

See the graph and references

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Ed 49 days ago
Booster period halves again
Just as I predicted

A few weeks ago I wrote a joke article, saying that booster dose frequency would double with each dose, going from 6 months, to 3 months, and so on, leading to a “singularity point” next July when the booster frequency becomes infinite.

Little did I know, that my joke so far is becoming “not a joke” and policymaking geniuses did indeed halve the booster period again, from 6 months to 3 months.

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Ed 34 days ago
Hong Kong researchers urge third COVID-19 shot 'as soon as possible'
HONG KONG, Dec 15 (Reuters) - Researchers in Hong Kong have urged people to get a third dose of COVID-19 vaccine as soon as possible, after a study showed insufficient antibodies were generated by the Sinovac (SVA.O) and BioNTech (22UAy.DE) products to fend off Omicron.

Tuesday's release of the results of a study by scientists in the microbiology department of the University of Hong Kong was the first published preliminary data on the impact of Sinovac's vaccine against the Omicron variant of coronavirus.

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